Search results for " precision"
showing 10 items of 145 documents
Molecular markers and endometrial cancer
2022
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ETP/GDOP Behavior Study for N-Sensors Arrays ina Multilateration Radar System
2009
In this paper, we evaluated the ETP (Expected Theoretical Precision) and GDOP (Geometric Dilution Of Precision) enhancement related to the number of sensors in a Multilateration radar system. An introduction about the principles of the Multilateration radar system basis operation is described, then, the formulation for evaluation the ETP/GDOP of the 3D positioning is shown. We observed that the ETP and GDOP enhance with the increase of the number of sensors. A substantial improvement was obtained until nine sensors but, for more sensors that improvement is reduced. Results for a 75km×75km area are shown, including LAM (Local Area Multilateration) and WAM (Wide Area Multilateration) settings…
Precision Medicine to Treat Advanced Gastroesophageal Adenocarcinoma: A Work in Progress
2020
Gastroesophageal adenocarcinoma (GEA) represents a heterogeneous disease and, when diagnosed as locally advanced or metastatic, it is characterized by poor prognosis. During the last few years, several molecular classifications have been proposed to try to personalize treatment for those patients diagnosed with advanced disease. Nevertheless, despite the great effort, precision medicine is still far from being a reality. The improvement in the molecular analysis due to the application of high throughput technologies based on DNA and RNA sequencing has opened a novel scenario leading to the personalization of treatment. The possibility to target epidermal growth factor receptor (HER)2, Claud…
A comparative study on sample preparation procedures for supplementary foods by ICP-OES: Green chemistry considerations
2015
An inductively coupled plasma optical emission (ICP-OES) method was developed for the simultaneous determination of major, minor and trace elements in food. Preliminary studies focused on selecting suitable operational conditions in order to provide the highest sensitivity and to maximize the number of analytes to be determined without spectral or matrix interference. Ruthenium and rhenium were evaluated as internal standards and samples were analyzed at different dilution levels. Furthermore, a comparative study was carried out by using three sample digestion methods, microwave-assisted digestion with HNO3/H2O2, dry ashing and dry ashing with Mg(NO3)2/MgO as an ashing aid. Adequate precisi…
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
2021
Abstract Background Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field. Results Leveraging DNA methylation and SNP data from more than 40,000 individuals, we identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We find evidence for shared genetic loci ass…
Weak effects of geolocators on small birds: A meta-analysis controlled for phylogeny and publication bias
2020
Abstract Currently, the deployment of tracking devices is one of the most frequently used approaches to study movement ecology of birds. Recent miniaturization of light‐level geolocators enabled studying small bird species whose migratory patterns were widely unknown. However, geolocators may reduce vital rates in tagged birds and may bias obtained movement data. There is a need for a thorough assessment of the potential tag effects on small birds, as previous meta‐analyses did not evaluate unpublished data and impact of multiple life‐history traits, focused mainly on large species and the number of published studies tagging small birds has increased substantially. We quantitatively reviewe…
Utilizzo di immagini in multispettrale da satellite per lo studio della variabilità di alcuni parametri vegetativi e produttivi del vigneto
2007
Ultrasound-assisted sequential extraction method for the evaluation of mobility of toxic elements in contaminated soils
2005
A method for the fast sequential extraction of toxic elements in contaminated soil samples using an ultrasonic water bath, followed by determination with inductively coupled plasma optical emission spectrometry (ICP-OES), was developed and compared with other methods introduced in the literature. The five-step sequential extraction (Tessier scheme) was shortened using ultrasound-assisted sequential extraction (UASE). The optimization of the five-step sequential extraction was based on the analysis of SRM 2710 using Tessiers’s method as a reference. Several extracting solutions with different sonication times and temperatures were tested in the optimization procedure. Concentrations of arsen…
Addition of thiourea and hydrochloric acid: Accurate nanogram level analysis of mercury in humic-rich natural waters by inductively coupled plasma ma…
2020
Abstract An analytical method was developed for the direct determination of total mercury in natural waters at low ng L−1 level by inductively coupled plasma mass spectrometry (ICP-MS). The presented method overcomes previously observed problems relating to poor spike recoveries by adding 0.12% thiourea in addition to 3% HCl to all samples and standards. The sample preparation is fast and easy to perform by the developed method since it requires only the addition of HCl and thiourea to the water samples. A very low instrument detection limit (0.4 ng L−1) was obtained without time-consuming preconcentration procedures. The accuracy and precision of the developed method were found excellent b…
Copper, iron and zinc determinations in human milk using FAAS with microwave digestion
2000
Abstract A method for determining copper, iron and zinc in human milk was optimized and validated. It includes microwave mineralization of the sample and measuring the elements by flame atomic absorption spectroscopy (FAAS). Only 2 ml of milk is needed, and the method is free of matrix interferences. The values obtained for the detection limits (0.07; 0.07; 0.11 μg/ml milk, for copper, iron and zinc) precision of the method, intra-assay (2.9; 5.2; 6.1%RSD for copper, iron and zinc) and accuracy, evaluated using recovery assays (98.8; 100.4; 95.9% for copper, iron and zinc) show that the method is useful for the purpose mentioned. Moreover, the method is rapid and simple, and the determinati…